Description

(S)-3-[(1E,7Z)-Hexadecan-7-Enylidene]-4,5-Dihydro-4-Hydroxy-5-Methylenefuran-2(3H)-One is a high-purity, optically active lactone derivative with a complex unsaturated hydrocarbon chain. This compound is valued for its role as a key chiral intermediate and building block in advanced organic synthesis, particularly for the development of bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemistry and high chemical fidelity for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially in the development of anti-inflammatory, antiviral, or other therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, or plant growth regulators where specific stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other specialty chemicals requiring complex, unsaturated lactone structures.
• Material Science Research: Investigated as a monomer or modifying agent for synthesizing novel polymers with specific functional properties.
• Academic & R&D: A valuable reagent for methodological studies in asymmetric synthesis, total synthesis of natural products, and catalysis research.

Basic Information

Product Name	(S)-3-[(1E,7Z)-Hexadecan-7-Enylidene]-4,5-Dihydro-4-Hydroxy-5-Methylenefuran-2(3H)-One
CAS No.	58940-66-2
Molecular Formula	C21H34O3
Molecular Weight	334.50 g/mol
Synonyms	(S)-3-[(1E,7Z)-7-Hexadecenylidene]-4-hydroxy-5-methylenedihydro-2(3H)-furanone; (S)-(-)-Aspicillin; (3S)-3-[(1E,7Z)-Hexadeca-1,7-dien-1-yl]-4-hydroxy-5-methylenedihydrofuran-2(3H)-one; Aspicillin; A fungal metabolite from Aspergillus ochraceus.
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this chiral compound, ensuring batch-to-batch consistency and high chemical purity. Our standard analytical suite includes chiral HPLC for enantiomeric excess verification, NMR for structural confirmation, and GC/HPLC for purity assessment. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥95% to ≥98%), chiral purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be sensitive to prolonged exposure to heat, light, and air. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC/GC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.