Description

2-(Trifluoromethyl)Propionaldehyde is a versatile fluorinated aldehyde building block, characterized by its reactive carbonyl group and trifluoromethyl substituent. This compound is valued for its ability to introduce both aldehyde functionality and fluorine atoms into target molecules, significantly altering their physical and chemical properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with unique surface properties and chemical resistance.
• Organic Synthesis: Employed in various name reactions (e.g., aldol condensations, reductive aminations) to construct complex, fluorinated molecular architectures.
• Liquid Crystal & Electronic Chemicals: Acts as a precursor for fluorinated components used in display technologies and electronic materials.

Basic Information

Product Name	2-(Trifluoromethyl)Propionaldehyde
CAS No.	58928-28-2
Molecular Formula	C4H5F3O
Molecular Weight	126.08 g/mol
Synonyms	3,3,3-Trifluoroisobutyraldehyde; 2-(Trifluoromethyl)propanal; 3,3,3-Trifluoro-2-methylpropanal; α-(Trifluoromethyl)propionaldehyde; TFMPA; Trifluoroisobutyraldehyde; 2-Methyl-3,3,3-trifluoropropanal
EINECS	Contact for details

Quality Control

Our production of 2-(Trifluoromethyl)Propionaldehyde adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Keep away from heat, sparks, and open flames. Isolate from strong bases, reducing agents, and oxidizing materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.