Description

2-(2-Chloro-Acetylamino)-Benzoic Acid Methyl Ester is a versatile and high-purity organic synthesis intermediate, essential for constructing complex molecular architectures. Its core value lies in its bifunctional reactivity, serving as a key building block for the development of advanced pharmaceuticals and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active ingredients and specialty compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzamide or anthranilate core structures.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and plant growth regulators, leveraging its reactive chloroacetyl and ester groups.
• Peptidomimetic Research: Serves as a valuable scaffold in medicinal chemistry for creating peptide analogs and enzyme inhibitors.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized organic dyes and colorants due to its aromatic benzoic acid derivative backbone.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions for carbon-carbon and carbon-heteroatom bond formation.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds.

Basic Information

Product Name	2-(2-Chloro-Acetylamino)-Benzoic Acid Methyl Ester
CAS No.	58915-18-7
Molecular Formula	C10H10ClNO3
Molecular Weight	227.64 g/mol
Synonyms	Methyl 2-(2-Chloroacetamido)benzoate; Methyl 2-[(2-Chloroacetyl)amino]benzoate; 2-(2-Chloroacetamido)benzoic Acid Methyl Ester; Benzoic acid, 2-[(2-chloroacetyl)amino]-, methyl ester; N-(2-Chloroacetyl)anthranilic Acid Methyl Ester; Methyl N-(2-Chloroacetyl)anthranilate; 58915-18-7; Methyl 2-(chloroacetamido)benzoate
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-Acetylamino)-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.