Description

Nalmefene Hydrochloride CAS NO 58895-64-0 is a potent, long-acting opioid receptor antagonist used primarily in pharmaceutical research and development. This compound is critical for advancing studies in addiction medicine and neuroscience, offering a key tool for modulating opioid pathways. It is essential for pharmaceutical manufacturers, research institutions, and laboratories focused on developing treatments for alcohol and opioid dependence.

Application

• Pharmaceutical Active Pharmaceutical Ingredient (API): Core component in the formulation of medications for alcohol and opioid dependence.
• Neuroscience Research: A vital tool for studying opioid receptor mechanisms, signal transduction, and neuropharmacology in preclinical models.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of pharmaceutical products.
• Clinical Trial Material: Serves as the investigational drug substance in studies evaluating new therapeutic applications.
• Biochemical Assay Development: Employed in creating in-vitro assays to screen for opioid receptor activity and drug interactions.

Basic Information

Product Name	Nalmefene Hydrochloride
CAS No.	58895-64-0
Molecular Formula	C21H25NO3·HCl
Molecular Weight	375.89 g/mol
Synonyms	Nalmefene HCl; (17-Cyclopropylmethyl-4,5α-epoxy-6-methylenemorphinan-3,14-diol) Hydrochloride; 6-Desoxy-6-methylenenaltrexone Hydrochloride; Nalmetrene Hydrochloride; ORF 11676; LY 135537; REVEX (brand name); Selincro (brand name)
EINECS	Contact for details

Quality Control

Our Nalmefene Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a dry environment and opened under conditions of low humidity to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.