Description

4-(4-(Trifluoromethyl)Phenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethylphenyl-substituted tetrahydropyridine structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) and other complex organic molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the tetrahydropyridine scaffold.
• Organic Synthesis Building Block: Serves as a versatile synthon for constructing complex molecules in medicinal and process chemistry due to its reactive amine hydrochloride functionality.
• Chemical Biology Probe Development: Employed in research to create molecular probes for studying enzyme inhibition and receptor binding mechanisms.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique electronic or surface properties.

Basic Information

Product Name	4-(4-(Trifluoromethyl)Phenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride
CAS No.	58778-52-2
Molecular Formula	C12H13ClF3N
Molecular Weight	263.68 g/mol
Synonyms	1,2,3,6-Tetrahydro-4-[4-(trifluoromethyl)phenyl]pyridine Hydrochloride; 4-(4-Trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine HCl; 4-(α,α,α-Trifluoro-p-tolyl)-1,2,3,6-tetrahydropyridine Hydrochloride; 4-(4-(Trifluoromethyl)phenyl)-3,6-dihydro-2H-pyridine Hydrochloride; 4-(p-Trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine Hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-(Trifluoromethyl)Phenyl)-1,2,3,6-Tetrahydropyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliable supply for sensitive pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.