Description

2-(Thien-2-Yl)Ethyl Isocyanate is a specialized organic building block featuring a reactive isocyanate group linked to a thiophene moiety via an ethylene spacer. This unique structure makes it a valuable intermediate for synthesizing functional polymers, advanced materials, and bioactive compounds where the thiophene unit imparts specific electronic or binding properties. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel urethanes, ureas, and other derivatives.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the thiophene ring for bioactivity.
• Specialty Polymer & Resin Production: Serves as a monomer or cross-linking agent for producing polyurethanes, polyureas, and coatings with enhanced thermal stability and specific material properties.
• Material Science Research: Employed in the development of advanced functional materials, including conductive polymers, liquid crystals, and organic semiconductors.
• Chemical Synthesis Reagent: A versatile reagent for introducing the 2-(thien-2-yl)ethyl carbamoyl group into molecules via reactions with amines, alcohols, and other nucleophiles.
• Bioconjugation & Probe Development: Useful in life sciences for labeling biomolecules or creating fluorescent probes and diagnostic agents.

Basic Information

Product Name	2-(Thien-2-Yl)Ethyl Isocyanate
CAS No.	58749-51-2
Molecular Formula	C7H7NOS
Molecular Weight	153.20 g/mol
Synonyms	2-(2-Isocyanatoethyl)thiophene; 2-Thiopheneethyl isocyanate; 2-(Thiophen-2-yl)ethyl isocyanate; 2-(2-Thienyl)ethyl isocyanate; β-(2-Thienyl)ethyl isocyanate; 1-Isocyanato-2-(2-thienyl)ethane; (2-Thien-2-ylethyl) isocyanate
EINECS	Contact for details

Quality Control

Our 2-(Thien-2-Yl)Ethyl Isocyanate is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from atmospheric moisture. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.