Description

Licochalcone B CAS NO 58749-23-8 is a bioactive chalcone derivative primarily extracted from the root of *Glycyrrhiza* species, notably licorice. This compound is valued for its potent antioxidant and anti-inflammatory properties, making it a significant ingredient in advanced cosmetic and pharmaceutical formulations. It is essential for manufacturers in the personal care, nutraceutical, and research sectors seeking natural, efficacious actives for skin health and therapeutic applications.

Application

• Cosmetic & Skincare Actives: Used in anti-aging serums, creams, and lotions for its antioxidant and skin-soothing benefits.
• Pharmaceutical Intermediates: Serves as a key starting material or active ingredient in the development of anti-inflammatory and chemopreventive drugs.
• Nutraceutical Supplements: Incorporated into formulations aimed at promoting cellular health and reducing oxidative stress.
• Academic & Industrial Research: A valuable reference standard and biochemical tool for studying chalcone pharmacology and natural product chemistry.
• Functional Food & Beverages: Potential application as a natural preservative and health-promoting additive.
• Hair Care Products: Formulated into shampoos and conditioners to support scalp health and protect hair follicles.

Basic Information

Product Name	Licochalcone B
CAS No.	58749-23-8
Molecular Formula	C16H14O5
Molecular Weight	286.28 g/mol
Synonyms	2',4'-Dihydroxy-6'-methoxy-3'-methylchalcone; (E)-1-(2,4-Dihydroxy-6-methoxy-3-methylphenyl)-3-phenyl-2-propen-1-one; Licochalcone-B; NSC 365039; Licorice Chalcone B; 3-Methyllicochalcone B
EINECS	Contact for details

Quality Control

Our Licochalcone B is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, identity confirmation (IR, NMR), and residual solvent analysis. Our quality system is designed to meet the stringent requirements of cosmetic ingredient and research-grade chemical supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.