Description

Licochalcone-A is a bioactive chalcone derivative primarily isolated from the root of *Glycyrrhiza* species, notably licorice. This compound is valued for its potent and multifaceted biological activities, making it a key ingredient in advanced formulations. It is particularly sought after by manufacturers in the cosmetic, nutraceutical, and pharmaceutical industries for its efficacy in skin care and wellness applications.

Application

• Cosmetic & Skincare Actives: Used as a primary active in anti-aging, brightening, and soothing serums and creams for its antioxidant and anti-inflammatory properties.
• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in the synthesis of novel therapeutic agents targeting inflammation and metabolic disorders.
• Nutraceutical Supplements: Incorporated into dietary supplements for its potential health-promoting benefits, including supporting metabolic health.
• Functional Food & Beverages: Applied as a natural bioactive component in health-focused food and drink products.
• Academic & Industrial Research: Utilized as a high-purity reference standard in pharmacological, biochemical, and cosmetic research.
• Hair Care Products: Formulated into shampoos and treatments for its potential to support scalp health and hair vitality.

Basic Information

Product Name	Licochalcone-A
CAS No.	58749-22-7
Molecular Formula	C21H22O4
Molecular Weight	338.40 g/mol
Synonyms	(E)-1-[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one; Licochalcone A; Licorice Chalcone A; NSC 348949; 2-Propen-1-one, 1-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (E)-
EINECS	Contact for details

Quality Control

Our Licochalcone-A is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for cosmetic and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.