Description

(3-Chloro-Phenyl)-Propynoic Acid Ethyl Ester is a versatile organic building block characterized by its phenyl ring substituted with a chloro group and an ethyl propynoate moiety. This compound is valued for its role as a key synthetic intermediate in the preparation of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing target structures via reactions like Sonogashira coupling or cyclization.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing arylacetylene or heterocyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Chemical Biology & Probe Development: Utilized as a tagging or labeling reagent due to the reactive alkyne group for click chemistry applications.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including catalysis and new bond-forming reactions.

Basic Information

Product Name	(3-Chloro-Phenyl)-Propynoic Acid Ethyl Ester
CAS No.	58686-68-3
Molecular Formula	C11H9ClO2
Molecular Weight	208.64 g/mol
Synonyms	Ethyl 3-(3-Chlorophenyl)propiolate; 3-Chlorophenylpropiolic Acid Ethyl Ester; Ethyl (3-Chlorophenyl)propynoate; 3-Chlorobenzeneacetic acid, α-ethynyl-, ethyl ester; m-Chlorophenylpropiolic Acid Ethyl Ester; Propiolic acid, 3-(3-chlorophenyl)-, ethyl ester; (3-Chlorophenyl)propynoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our (3-Chloro-Phenyl)-Propynoic Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.