Description

Nomegestrol 17-Acetate is a synthetic progestogen steroid derivative, widely recognized for its high biological activity and specificity. This compound is a critical active pharmaceutical ingredient (API) in the development and manufacturing of advanced hormonal therapies. It is primarily utilized by pharmaceutical companies and research institutions focused on gynecological health, oncology, and endocrinology.

Application

• Pharmaceutical API: Core active ingredient in hormonal contraceptives and hormone replacement therapies (HRT).
• Gynecological Treatments: Used in formulations for managing endometriosis, uterine fibroids, and menstrual disorders.
• Oncological Research: Investigated for potential applications in hormone-sensitive cancers, such as breast and endometrial cancer.
• Endocrinology Research: Serves as a reference standard and key intermediate in steroid hormone research and development.
• Veterinary Medicine: Applied in reproductive control and treatment protocols for animals.
• Intermediate Synthesis: Used as a high-purity building block for synthesizing more complex steroid molecules.

Basic Information

Product Name	Nomegestrol 17-Acetate
CAS No.	58652-20-3
Molecular Formula	C₂₃H₃₀O₄
Molecular Weight	370.48 g/mol
Synonyms	Nomegestrol acetate; 17α-Acetoxy-6-methyl-19-norpregna-4,6-diene-3,20-dione; 6-Methyl-17α-acetoxy-19-nor-4,6-pregnadiene-3,20-dione; Lutenyl; Org 30659; SH T00166AA; (17α)-17-(Acetyloxy)-6-methyl-19-norpregna-4,6-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our Nomegestrol 17-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) are available upon request, detailing compliance with relevant internal and customer-specific standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.