Description

3-(Isocyanomethyl)Pyridine is a versatile and reactive heterocyclic building block, specifically an isocyanate derivative of pyridine. This compound matters for its unique bifunctional reactivity, offering both the aromatic nitrogen of the pyridine ring and the highly electrophilic isocyanate group, enabling its use in the synthesis of complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients, as well as in material science for creating specialized polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the pyridine moiety often contributes to biological activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing polyurethanes, polyureas, and other specialty polymers with enhanced thermal or chemical resistance.
• Ligand & Catalyst Development: The pyridine nitrogen acts as a coordination site for metals, making it useful for constructing chelating ligands in catalytic systems.
• Chemical Research & Development: Employed in organic synthesis for constructing heterocyclic compounds, urea derivatives, and carbamates via reactions with amines and alcohols.
• Surface Modification: Can be used to functionalize surfaces or materials by introducing reactive isocyanate groups for further conjugation.

Basic Information

Product Name	3-(Isocyanomethyl)Pyridine
CAS No.	58644-55-6
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	3-Pyridinemethanol, isocyanato-; Isocyanatomethylpyridine; 3-(Isocyanatomethyl)pyridine; 3-Pyridylmethyl isocyanate; (Pyridin-3-yl)methyl isocyanate; 3-Pyridylmethylisocyanate; 3-PIC; 3-Pyridinemethyl isocyanate
EINECS	Contact for details

Quality Control

Our 3-(Isocyanomethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.