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Ethyl 2-(6'-Cyano-5'-Oxo-3',5'-Dihydro-2'H-Spiro[[1,3]Dioxolane-2,1'-Indolizine]-7'-Yl)Acetate CAS NO 58610-65-4


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CAS No.:58610-65-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 2-(6'-Cyano-5'-Oxo-3',5'-Dihydro-2'H-Spiro[[1,3]Dioxolane-2,1'-Indolizine]-7'-Yl)Acetate is a sophisticated spirocyclic indolizine derivative, a high-value chemical intermediate prized for its unique molecular architecture. This compound is critical for advanced organic synthesis, serving as a versatile building block for constructing complex heterocyclic frameworks. It is primarily sought by pharmaceutical R&D and fine chemical manufacturers for developing novel active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
  • Agrochemical Research: Used in developing advanced active ingredients for crop protection with novel modes of action.
  • Material Science: Building block for creating specialty polymers, dyes, or organic electronic materials due to its fused ring system.
  • Academic & Contract Research: Essential reagent for methodological studies in organic chemistry and heterocyclic compound synthesis.
  • Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological processes.

Basic Information

Product Name Ethyl 2-(6'-Cyano-5'-Oxo-3',5'-Dihydro-2'H-Spiro[[1,3]Dioxolane-2,1'-Indolizine]-7'-Yl)Acetate
CAS No. 58610-65-4
Molecular Formula C17H16N2O5
Molecular Weight 328.32 g/mol
Synonyms Ethyl (6'-Cyano-5'-oxo-3',5'-dihydro-2'H-spiro[1,3-dioxolane-2,1'-indolizine]-7'-yl)acetate; 7-(Ethoxycarbonylmethyl)-6-cyano-5-oxo-2,3,5,8-tetrahydrospiro[indolizine-1,2'-[1,3]dioxolane]; Spiro[1,3-dioxolane-2,1'-indolizine] acetic acid derivative; 58610-65-4; Acetic acid, 2-(6-cyano-5-oxo-3,5-dihydro-2H-spiro[1,3-dioxolane-2,1'-indolizine]-7-yl)-, ethyl ester
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Quality Control

Our Ethyl 2-(6'-Cyano-5'-Oxo-3',5'-Dihydro-2'H-Spiro[[1,3]Dioxolane-2,1'-Indolizine]-7'-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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