Description

2,3,6-Trichloro-5-Methylpyridine is a halogenated pyridine derivative that serves as a crucial advanced intermediate in organic synthesis. Its value lies in its unique substitution pattern, which makes it a versatile building block for constructing complex molecules, particularly in the agrochemical and pharmaceutical sectors. This compound is primarily needed by R&D chemists and process development teams in fine chemical manufacturing for the production of specialized active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging its pyridine core for biological activity.
• Pharmaceutical Building Block: Used in medicinal chemistry research for the development of novel drug candidates, especially those targeting neurological and anti-infective pathways.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of advanced materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Stille) to create more complex biaryl structures.
• Nucleophilic Substitution Scaffold: The chlorine atoms provide reactive sites for displacement with various nucleophiles to generate diverse pyridine libraries.

Basic Information

Product Name	2,3,6-Trichloro-5-Methylpyridine
CAS No.	58584-95-5
Molecular Formula	C6H4Cl3N
Molecular Weight	196.46 g/mol
Synonyms	5-Methyl-2,3,6-trichloropyridine; 2,3,6-Trichloro-5-picoline; NSC 403116; 2,3,6-Trichloro-5-methylpyridine; Trichloromethylpyridine
EINECS	Contact for details

Quality Control

Our 2,3,6-Trichloro-5-Methylpyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.