Description

3-(Hydroxymethyl)Isonicotinonitrile is a versatile pyridine derivative and a valuable bifunctional building block in organic synthesis, combining a reactive hydroxymethyl group with a nitrile functionality. This compound is crucial for researchers and manufacturers requiring high-purity intermediates to construct complex molecular architectures with precision. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the research and production of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes and tags for studying biological processes and drug-target interactions.
• Custom Synthesis and R&D: An essential building block for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	3-(Hydroxymethyl)Isonicotinonitrile
CAS No.	58553-51-8
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	4-Cyano-3-pyridinemethanol; 4-Cyanopyridin-3-ylmethanol; 3-Pyridinemethanol, 4-cyano-; Isonicotinonitrile, 3-(hydroxymethyl)-; 3-(Hydroxymethyl)-4-cyanopyridine; 4-Cyano-3-(hydroxymethyl)pyridine; 3-Hydroxymethyl-isonicotinonitrile; 3-(Hydroxymethyl)pyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-(Hydroxymethyl)Isonicotinonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.