Description

2-Amino-5-Chloronicotinamide is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its core value proposition lies in its role as a key building block for constructing complex heterocyclic compounds, particularly in the pharmaceutical sector. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its chloronicotinamide structure.
• Fine Chemical Production: Serves as a specialized building block for creating complex molecules used in material science and specialty chemistry.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical reactions and synthesizing libraries of compounds for biological screening.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in manufacturing processes.

Basic Information

Item	Detail
Product Name	2-Amino-5-Chloronicotinamide
CAS No.	58483-97-9
Molecular Formula	C6H6ClN3O
Molecular Weight	171.58 g/mol
Synonyms	5-Chloro-2-aminonicotinamide; 2-Amino-5-chloro-3-pyridinecarboxamide; 5-Chloro-2-aminopyridine-3-carboxamide; 3-Carbamoyl-5-chloropyridin-2-amine; 5-Chloro-2-aminonicotinic acid amide; 2-Amino-5-chloronicotinic acid amide; 5-Chloro-2-aminonicotinamide; 2-Amino-5-chloro-3-carbamoylpyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloronicotinamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to cGMP principles and relevant ICH guidelines ensures a reliable supply for demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.