Description

5-Amino-2-Chloropyridine-4-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its molecular structure, featuring both amino and carboxylic acid functional groups on a chlorinated pyridine core, makes it a versatile intermediate for constructing complex molecules. This compound is particularly valuable for research and development in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging its heterocyclic structure for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functional organic materials, such as dyes, pigments, and organic electronic components.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects requiring precise, high-quality heterocyclic intermediates.

Basic Information

Product Name	5-Amino-2-Chloropyridine-4-Carboxylic Acid
CAS No.	58483-95-7
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	2-Chloro-5-aminopyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 5-amino-2-chloro-; 5-Amino-2-chloroisonicotinic acid; 2-Chloro-5-aminopyridine-4-carboxylic acid; 5-Amino-2-chloro-4-pyridinecarboxylic acid; 5-Amino-2-chloro-4-carboxypyridine; 2-Chloro-5-amino-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloropyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.