Description

Methyl 2-(Hydroxymethyl)Isonicotinate is a versatile pyridine derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its bifunctional structure, featuring both an ester and a hydroxymethyl group on the pyridine ring, makes it a valuable building block for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of functional polymers and organic electronic materials due to its modifiable aromatic system.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Methyl 2-(Hydroxymethyl)Isonicotinate
CAS No.	58481-17-7
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	Methyl 2-(hydroxymethyl)isonicotinate; 2-(Hydroxymethyl)isonicotinic acid methyl ester; Methyl 2-(hydroxymethyl)-4-pyridinecarboxylate; 4-Pyridinecarboxylic acid, 2-(hydroxymethyl)-, methyl ester; Isonicotinic acid, 2-(hydroxymethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(Hydroxymethyl)Isonicotinate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP for pharmaceutical intermediates where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.