Description

Methyl 1-Phenylcyclobutane-1-Carboxylate is a specialized organic ester building block featuring a phenyl-substituted cyclobutane ring. This compound matters as a versatile chiral intermediate in advanced organic synthesis, offering a constrained, four-membered ring structure that is valuable for modulating molecular conformation and properties. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the preparation of advanced pesticide and herbicide molecules, where the cyclobutane scaffold can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers or additives for specialty polymers with tailored thermal or mechanical properties.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Methyl 1-Phenylcyclobutane-1-Carboxylate
CAS No.	58469-03-7
Molecular Formula	C12H14O2
Molecular Weight	190.24 g/mol
Synonyms	1-Phenylcyclobutane-1-carboxylic acid methyl ester; Methyl 1-phenyl-1-cyclobutanecarboxylate; 1-Cyclobutanecarboxylic acid, 1-phenyl-, methyl ester; Methyl α-phenylcyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 1-Phenylcyclobutane-1-Carboxylate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.