Description

1-Allyl-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a reactive isocyanide group. This compound matters for its versatility as a key intermediate in multi-component reactions, enabling the efficient synthesis of complex heterocyclic scaffolds. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular libraries and active ingredients.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of complex heterocycles via Passerini and Ugi multi-component reactions for drug discovery programs.
• Agrochemical Research: Used to build novel pesticidal and herbicidal compounds with unique structural motifs.
• Material Science: Serves as a precursor for functional polymers and ligands with tailored properties.
• Academic & R&D Laboratories: Employed in methodological development and the exploration of new synthetic pathways in organic chemistry.
• Peptidomimetics Synthesis: Facilitates the creation of peptide-like structures with enhanced stability and bioavailability.

Basic Information

Product Name	1-Allyl-1-Tosylmethyl Isocyanide
CAS No.	58379-85-4
Molecular Formula	C₁₂H₁₃NO₂S
Molecular Weight	235.30 g/mol
Synonyms	1-Allyl-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-Allyl-1-(p-tolylsulfonyl)methyl isocyanide; 1-Allyl-1-(tosylmethyl)isocyanide; Allyl tosylmethyl isocyanide; ATMI; Isocyanide, (allyl)(p-toluenesulfonyl)methyl-; (Allyl)(4-methylphenylsulfonyl)methyl isocyanide
EINECS	Contact for details

Quality Control

Our 1-Allyl-1-Tosylmethyl Isocyanide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, well-ventilated place. Keep away from heat, sparks, and open flame. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.