Description

1-Isopropyl-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a reactive isocyanide group and a tosyl-protected methylene unit. This compound is valued for its versatility as a key intermediate in multi-component reactions, enabling the efficient synthesis of complex heterocyclic scaffolds and functionalized molecules. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular libraries and active ingredients.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of heterocyclic compounds via Passerini and Ugi multi-component reactions for drug discovery programs.
• Agrochemical Research: Used to build novel pesticidal and herbicidal agents with complex ring systems.
• Material Science: Serves as a precursor for functionalized polymers and advanced organic materials.
• Academic & R&D: A valuable tool in methodological organic chemistry research for developing new synthetic pathways.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	1-Isopropyl-1-Tosylmethyl Isocyanide
CAS No.	58379-84-3
Molecular Formula	C12H15NO2S
Molecular Weight	237.32 g/mol
Synonyms	1-Isopropyl-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-Tosyl-2-methylpropyl isocyanide; 1-Isopropyl-1-(p-tolylsulfonyl)methyl isocyanide; TosMIC isopropyl derivative; (1-Isopropyl-1-tosylmethyl)isocyanide; p-Toluenesulfonylmethyl isocyanide isopropyl analog; Isopropyl tosylmethyl isocyanide
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-1-Tosylmethyl Isocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.