Description

n-Hydroxy Amobarbital is a chemically modified derivative of the barbiturate class, specifically amobarbital. This compound is of significant interest in pharmaceutical research and development for its potential as a key synthetic intermediate or a metabolite for analytical studies. It serves the needs of research institutions, pharmaceutical development laboratories, and chemical manufacturers focused on central nervous system (CNS) active agents, analytical standards, and specialized fine chemical synthesis.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial building block in the synthesis and development of novel barbiturate-derived compounds or prodrugs.
• Metabolite Reference Standard: Used in analytical chemistry and bioanalysis as a reference standard for studying the metabolism and pharmacokinetics of amobarbital.
• Biochemical Research: Employed in in-vitro studies to investigate the structure-activity relationships (SAR) of barbiturates and their interaction with biological targets.
• Chemical Synthesis: Acts as a specialized reagent for introducing the N-hydroxy functional group into complex molecular architectures.
• Analytical Method Development: Utilized in laboratories to develop and validate chromatographic (HPLC, GC) or spectroscopic methods for barbiturate detection and quantification.

Basic Information

Product Name	n-Hydroxy Amobarbital
CAS No.	58359-49-2
Molecular Formula	C11H18N2O4
Molecular Weight	242.27 g/mol
Synonyms	5-Ethyl-5-(3-methylbutyl)-1-hydroxy-1,3-diazinane-2,4,6-trione; 1-Hydroxyamobarbital; N-Hydroxy-5-ethyl-5-isopentylbarbituric acid; Amobarbital N-oxide; Amobarbital 1-N-oxide; 5-Ethyl-5-isopentyl-1-hydroxybarbituric acid
EINECS	Contact for details

Quality Control

Our n-Hydroxy Amobarbital is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.