Description

3-[Bis(2-Chloroethyl)Amino]-p-Toluic Acid 2-(Diethylamino)Ethyl Ester is a specialized organic compound belonging to the class of nitrogen mustard derivatives, characterized by its unique bifunctional alkylating properties. This compound is of significant interest for its role as a key synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and chemical manufacturers engaged in the synthesis of targeted therapeutic agents and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nitrogen mustard-based prodrugs and targeted chemotherapeutic agents.
• Biochemical Research: Used in the study of alkylating agents and their mechanisms of action on DNA and cellular components.
• Anticancer Drug Development: Serves as a precursor in the research and development of novel cytostatic compounds.
• Organic Synthesis: Employed in the preparation of complex esters and amides for structure-activity relationship (SAR) studies.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-[Bis(2-Chloroethyl)Amino]-p-Toluic Acid 2-(Diethylamino)Ethyl Ester
CAS No.	58278-35-6
Molecular Formula	C18H28Cl2N2O2
Molecular Weight	375.34 g/mol
Synonyms	2-{4-[Bis(2-chloroethyl)amino]benzoyl}oxy-N,N-diethylethanaminium; 2-(Diethylamino)ethyl 4-[bis(2-chloroethyl)amino]benzoate; NSC 113942; p-[Bis(2-chloroethyl)amino]benzoic Acid 2-(Diethylamino)ethyl Ester; 4-[Bis(2-chloroethyl)amino]benzoic Acid 2-(Diethylamino)ethyl Ester; Ester of 4-[bis(2-chloroethyl)amino]benzoic acid with 2-(diethylamino)ethanol; Chlorambucil Diethylaminoethyl Ester (analog)
EINECS	Contact for details

Quality Control

Our production of 3-[Bis(2-Chloroethyl)Amino]-p-Toluic Acid 2-(Diethylamino)Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the exacting standards required for research-grade and pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.