Description

5-Chloro-2-Phenylpyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining a chlorinated pyridine ring with a phenyl substituent, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the chloropyridine moiety is a common bioactive scaffold.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or components for OLEDs, due to its aromatic and electron-deficient character.
• Chemical Research & Development: A fundamental building block for medicinal chemistry programs and structure-activity relationship (SAR) studies in drug discovery.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for the production of bespoke compounds and proprietary intermediates under cGMP or ISO standards.

Basic Information

Product Name	5-Chloro-2-Phenylpyridine
CAS No.	58254-76-5
Molecular Formula	C11H8ClN
Molecular Weight	189.64 g/mol
Synonyms	2-Phenyl-5-chloropyridine; 5-Chloro-2-phenylpyridine; 5-Chloro-2-phenylpyridine; 2-(5-Chloropyridinyl)benzene; 5-Chloro-2-pyridinylbenzene; (5-Chloro-2-pyridinyl)benzene; 5-Chloro-2-(phenyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Phenylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with ISO guidelines, and we can support development projects requiring material produced under more stringent controls. Specifications are tailored to meet the rigorous demands of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.