Description

Ethyl 5-Chloro-6-Hydroxynicotinate is a high-purity, versatile nicotinate derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated hydroxypyridine structure, which enables precise molecular modifications in complex chemical pathways. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent synthesis.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated pyridine core for bioactive molecule construction.
• Chemical Research: Serves as a versatile precursor in academic and industrial R&D for exploring new heterocyclic compounds and reaction methodologies.
• Material Science: Potential building block for creating functionalized organic materials and ligands for metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for various high-value industrial applications.

Basic Information

Product Name	Ethyl 5-Chloro-6-Hydroxynicotinate
CAS No.	58236-73-0
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	5-Chloro-6-hydroxy-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-chloro-6-hydroxy-3-pyridinecarboxylate; 5-Chloro-6-hydroxynicotinic acid ethyl ester; 3-Pyridinecarboxylic acid, 5-chloro-6-hydroxy-, ethyl ester; 6-Hydroxy-5-chloronicotinic acid ethyl ester; 5-Chloro-6-hydroxypyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-6-Hydroxynicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.