Description

3-Bromo-2-(Bromomethyl)-4,6-Dimethoxybenzoic Acid Methyl Ester is a high-purity, multi-functional brominated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a versatile intermediate in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries seeking to introduce specific brominated motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting bromine-containing heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, where its bromine atoms can be pivotal for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized aromatic monomers for advanced polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on halogen dance reactions and palladium-catalyzed transformations.

Basic Information

Product Name	3-Bromo-2-(Bromomethyl)-4,6-Dimethoxybenzoic Acid Methyl Ester
CAS No.	58137-74-9
Molecular Formula	C11H12Br2O4
Molecular Weight	368.02 g/mol
Synonyms	Methyl 3-Bromo-2-(bromomethyl)-4,6-dimethoxybenzoate; 2-(Bromomethyl)-3-bromo-4,6-dimethoxybenzoic Acid Methyl Ester; Benzoic acid, 3-bromo-2-(bromomethyl)-4,6-dimethoxy-, methyl ester; Methyl 2-(bromomethyl)-3-bromo-4,6-dimethoxybenzoate; 4,6-Dimethoxy-3-bromo-2-bromomethylbenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(Bromomethyl)-4,6-Dimethoxybenzoic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature (store away from light), the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.