Description

Cyclopentanecarboxylic Acid, 1-Amino-3-Methyl-, Hydrate (2:1), (1R-Trans)- (9Ci) is a chiral, non-proteinogenic amino acid derivative with a constrained cyclopentane ring structure. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its ability to impart conformational rigidity and stereochemical control. It is primarily utilized by pharmaceutical and agrochemical R&D sectors for the development of novel active ingredients, including peptidomimetics and small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in peptidomimetic and protease inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and catalysts in enantioselective synthesis.
• Peptide Chemistry: Incorporated into peptide chains to study structure-activity relationships (SAR) and enhance metabolic stability.
• Chemical Biology Research: Used as a molecular probe or building block in the study of biological pathways and protein interactions.
• Fine Chemical Production: An intermediate for the manufacture of specialty chemicals requiring a specific stereochemical configuration.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 1-Amino-3-Methyl-, Hydrate (2:1), (1R-Trans)- (9Ci)
CAS No.	58073-30-6
Molecular Formula	C7H13NO2 • 1/2H2O
Molecular Weight	146.19 g/mol (Anhydrous basis)
Synonyms	(1R,3S)-1-Amino-3-methylcyclopentanecarboxylic acid hydrate; (1R,3S)-1-Amino-3-methylcyclopentane-1-carboxylic acid hemihydrate; (1R-trans)-1-Amino-3-methylcyclopentanecarboxylic Acid Hydrate; trans-1-Amino-3-methylcyclopentanecarboxylic acid; AMPC hydrate; (1R,3S)-AMPC hemihydrate
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarboxylic Acid, 1-Amino-3-Methyl-, Hydrate (2:1), (1R-Trans)- (9Ci) adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), assay, and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	3.0 - 6.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.