Description

(14β,20β,22R,25R)-3β-Hydroxy-5α-Spirost-8-En-11-One is a high-purity, steroidal sapogenin derivative with a defined stereochemistry. This compound serves as a critical intermediate in the synthesis of complex steroid-based pharmaceuticals and fine chemicals, offering a reliable building block for research and development. It is essential for pharmaceutical manufacturers, research institutions, and fine chemical producers focused on developing novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and development of new drug candidates targeting hormone receptors.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring specific steroidal frameworks.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	(14β,20β,22R,25R)-3β-Hydroxy-5α-Spirost-8-En-11-One
CAS No.	58072-54-1
Molecular Formula	C27H40O4
Molecular Weight	428.61 g/mol
Synonyms	11-Ketotigogenin; 3β-Hydroxy-5α-spirost-8-en-11-one; Tigogenone; (25R)-3β-Hydroxy-5α-spirost-8-en-11-one; 5α-Spirost-8-en-11-one, 3β-hydroxy-, (3β,5α,14β,20β,22R,25R)-; Tigogenin-11-one
EINECS	Contact for details

Quality Control

Our (14β,20β,22R,25R)-3β-Hydroxy-5α-Spirost-8-En-11-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.