Description

Ethyl 8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indole-2-Carboxylate is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of novel pharmaceutical candidates, particularly those targeting central nervous system disorders. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development for new drug entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, especially those with indole and tetrahydro-β-carboline scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Neurological Drug Development: Serves as a core structure for developing potential therapeutics targeting serotonin receptors and related neurological pathways.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological mechanisms and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds under cGMP conditions.

Basic Information

Product Name	Ethyl 8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indole-2-Carboxylate
CAS No.	58038-66-7
Molecular Formula	C14H15FN2O2
Molecular Weight	262.28 g/mol
Synonyms	8-Fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indole-2-carboxylic acid ethyl ester; Ethyl 8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-2-carboxylate; 8-Fluoro-2-carbethoxy-1,2,3,4-tetrahydro-9H-pyrido[4,3-b]indole; 8-Fluoro-2-ethoxycarbonyl-1,2,3,4-tetrahydro-9H-pyrido[4,3-b]indole; 58038-66-7; FC-1012 (Potential Research Code)
EINECS	Contact for details

Quality Control

Our Ethyl 8-Fluoro-1,3,4,5-Tetrahydro-2H-Pyrido[4,3-B]Indole-2-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.