Description

2-[(Trifluoroacetyl)Amino]Hexanedioic Acid Bis(1-Methylpropyl) Ester is a specialized synthetic intermediate featuring a trifluoroacetyl-protected amino group and diester functionality. This compound is valued for its role in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of fluorine atoms and specific ester groups is critical for modulating biological activity and physicochemical properties. Key industries that utilize this high-purity building block include pharmaceutical R&D, agrochemical manufacturing, and advanced material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoroacetyl group can influence potency and environmental persistence.
• Peptide Mimetics & Prodrug Development: The protected amino acid ester structure makes it suitable for constructing peptide analogs and designing prodrug strategies to improve drug delivery.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and other sophisticated chemical transformations.
• Material Science Research: Acts as a monomer or modifier in the development of specialty polymers and coatings with tailored surface properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological mechanisms and diagnostic applications.

Basic Information

Product Name	2-[(Trifluoroacetyl)Amino]Hexanedioic Acid Bis(1-Methylpropyl) Ester
CAS No.	57983-10-5
Molecular Formula	C16H26F3NO5
Molecular Weight	369.38 g/mol
Synonyms	Bis(sec-butyl) 2-[(trifluoroacetyl)amino]hexanedioate; Di-sec-butyl 2-(trifluoroacetamido)adipate; 2-(Trifluoroacetamido)adipic Acid Di-sec-butyl Ester; Hexanedioic acid, 2-[(trifluoroacetyl)amino]-, bis(1-methylpropyl) ester; Adipic acid derivative, N-trifluoroacetyl-, di-sec-butyl ester; TFAA-Adipic acid di-sec-butyl ester; N-Trifluoroacetyl-L-α-aminoadipic acid di-sec-butyl ester (potential stereoisomer)
EINECS	Contact for details

Quality Control

Our production of 2-[(Trifluoroacetyl)Amino]Hexanedioic Acid Bis(1-Methylpropyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials undergo comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR, MS). A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.