Description

Ethyl 4-(3-Nitrophenyl)-2,4-Dioxobutanoate is a specialized organic compound featuring a β-diketone ester moiety linked to a nitrophenyl group, making it a valuable synthetic intermediate. This structure is crucial for constructing complex molecules in advanced chemical synthesis, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other high-value heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing fused heterocyclic systems.
• Agrochemical Synthesis: Used in research for developing novel herbicides, fungicides, and insecticides that require specific nitrophenyl-substituted structures.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and advanced organic materials where the nitro and diketone functionalities are essential.
• Academic & Industrial Research: Employed in methodological studies and as a model substrate for developing new organic reactions, such as cyclocondensations.
• Coordination Chemistry: The β-diketone moiety can act as a ligand for metal ions, useful in creating catalysts or metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethyl 4-(3-Nitrophenyl)-2,4-Dioxobutanoate
CAS No.	57961-49-6
Molecular Formula	C₁₂H₁₁NO₆
Molecular Weight	265.22 g/mol
Synonyms	Ethyl 3-(3-nitrobenzoyl)pyruvate; 4-(3-Nitrophenyl)-2,4-dioxobutanoic acid ethyl ester; 3-Nitrobenzoylpyruvic acid ethyl ester; Ethyl (3-nitrobenzoyl)pyruvate; Ethyl 4-(3-nitrophenyl)-2,4-dioxobutanoate; 2,4-Dioxo-4-(3-nitrophenyl)butyric acid ethyl ester; 1-Ethoxy-1,3-bis(3-nitrophenyl)-1,3-propanedione (tautomeric form); Ethyl β-(3-nitrobenzoyl)pyruvate
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-(3-Nitrophenyl)-2,4-Dioxobutanoate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.