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9-Oxo-11Alpha,15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, (4-Benzoylamino) Phenyl Ester CAS NO 57790-53-1


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CAS No.:57790-53-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9-Oxo-11Alpha,15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, (4-Benzoylamino) Phenyl Ester is a chemically modified prostaglandin derivative, specifically a phenyl ester analog of a key prostaglandin intermediate. This compound is of significant value as a high-purity reference standard and a critical synthetic intermediate in advanced pharmaceutical research and development. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics targeting inflammatory pathways, cardiovascular function, and other prostaglandin-mediated processes.

Application

  • Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in drug substance and product testing.
  • Biochemical Research: Serves as a key reagent and probe in studying prostaglandin biosynthesis, receptor binding, and signal transduction mechanisms.
  • Advanced Synthetic Intermediate: Utilized in the multi-step synthesis of more complex prostaglandin analogs and drug candidates with potential therapeutic applications.
  • Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the fate of related drug compounds in biological systems.
  • Enzyme Inhibition Assays: Acts as a substrate or inhibitor in assays targeting enzymes like cyclooxygenase (COX) for drug discovery screening.

Basic Information

Product Name 9-Oxo-11Alpha,15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, (4-Benzoylamino) Phenyl Ester
CAS No. 57790-53-1
Molecular Formula C35H43NO6
Molecular Weight 573.73 g/mol
Synonyms 11α,15S-Dihydroxy-9-oxoprosta-5Z,13E-dien-1-oic Acid 4-(Benzoylamino)phenyl Ester; PGE2 Phenyl Ester Derivative; (4-Benzamidophenyl) 11α,15-Dihydroxy-9-oxoprosta-5Z,13E-dien-1-oate; Prostaglandin E2 (PGE2) Phenyl Ester Analog; 9-Keto-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic Acid (4-Benzoylamino)phenyl Ester; Benzamidophenyl Prostaglandin Ester
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Quality Control

Our 9-Oxo-11Alpha,15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, (4-Benzoylamino) Phenyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines for the manufacture of advanced pharmaceutical intermediates, ensuring traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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