Description

1,5-Bis(Succinimidooxycarbonyloxy) Pentane is a specialized bifunctional cross-linking agent, widely recognized by its CAS number 57772-64-2. This compound is valued for its ability to form stable covalent bonds with primary amines, making it a critical reagent in advanced bioconjugation and material science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and polymer industries for creating stable, functionalized biomolecules and advanced materials.

Application

• Bioconjugation Reagent: For the covalent attachment of proteins, peptides, antibodies, or enzymes to various surfaces, particles, or other biomolecules.
• Diagnostic Assay Development: Used in the manufacture of immunoassays (e.g., ELISA) and biosensors to immobilize capture antibodies or antigens.
• Drug Delivery Systems: As a linker for attaching therapeutic agents (drugs, toxins) to targeting molecules like antibodies or polymers.
• Polymer Modification: Cross-linking agent for synthesizing or functionalizing hydrogels, dendrimers, and other polymeric materials with amine-reactive sites.
• Affinity Chromatography: Immobilization ligand for creating specialized chromatography resins used in protein purification.
• Surface Chemistry: Functionalization of glass, silicon, or gold surfaces for microarray technology or biochip fabrication.

Basic Information

Product Name	1,5-Bis(Succinimidooxycarbonyloxy) Pentane
CAS No.	57772-64-2
Molecular Formula	C15H18N2O10
Molecular Weight	386.31 g/mol
Synonyms	1,5-Bis[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,5-dioxopentane; Disuccinimidyl Glutarate; DSG; Bis(succinimidyl) Glutarate; N,N'-Disuccinimidyl Glutarate; Glutaric Acid Bis(N-hydroxysuccinimide Ester); Bis(N-succinimidyl) Glutarate; DSC (in some contexts); BS(PEG)5 (Note: This is a common trade name for a PEGylated analog, but often used in searches for this compound class).
EINECS	Contact for details

Quality Control

Our 1,5-Bis(Succinimidooxycarbonyloxy) Pentane is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.