Description

2-[(Trimethylsilyl)Methyl]Benzenemethanol is a versatile organosilicon compound featuring both a benzylic alcohol and a trimethylsilylmethyl group, making it a valuable synthon in advanced organic synthesis. Its primary commercial value lies in its dual functionality, which allows it to serve as a key protected intermediate or building block for constructing complex molecular architectures. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, specialized intermediates for innovative product development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing silicon-containing pharmacophores or protected alcohol functionalities.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the silicon group can influence bioavailability and stability.
• Organometallic Catalyst Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis, including cross-coupling and hydrogenation reactions.
• Advanced Material Monomer: Employed in the development of specialty polymers, silicones, and hybrid organic-inorganic materials with tailored properties.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the (trimethylsilyl)methyl group into aromatic systems, a valuable transformation in medicinal and process chemistry.
• Protecting Group Strategy: The silyl group can act as a protective moiety for the benzylic position during multi-step synthetic sequences.

Basic Information

Product Name	2-[(Trimethylsilyl)Methyl]Benzenemethanol
CAS No.	57754-01-5
Molecular Formula	C11H18OSi
Molecular Weight	194.35 g/mol
Synonyms	α-(Trimethylsilyl)-o-tolylmethanol; (2-((Trimethylsilyl)methyl)phenyl)methanol; Benzenemethanol, 2-[(trimethylsilyl)methyl]-; o-((Trimethylsilyl)methyl)benzyl alcohol; 2-(Trimethylsilylmethyl)benzyl Alcohol; 2-(Trimethylsilylmethyl)benzenemethanol
EINECS	Contact for details

Quality Control

Every batch of 2-[(Trimethylsilyl)Methyl]Benzenemethanol is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your critical applications. Our standard grade typically meets a purity specification of ≥95% (by GC or HPLC), but higher purity grades are available. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.