Description

1-(Benzyloxycarbonyl)Benzotriazole is a versatile benzotriazole-based reagent primarily used as a protective group agent and coupling intermediate in organic synthesis. This compound is valued for its role in facilitating the formation of amide bonds and protecting amine functionalities under mild conditions. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and complex molecules.

Application

• Peptide Synthesis: Acts as a coupling reagent and a protecting group for amino acids in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Manufacturing: Used in the production of herbicides, fungicides, and insecticides where specific amide linkages are required.
• Polymer Chemistry: Employed in the synthesis of polyamides and other specialty polymers requiring controlled monomer coupling.
• Bioconjugation: Facilitates the labeling and modification of biomolecules for diagnostic and research applications.
• Organic Synthesis Reagent: A valuable tool for chemists in constructing complex molecular architectures, particularly in academic and R&D settings.

Basic Information

Product Name	1-(Benzyloxycarbonyl)Benzotriazole
CAS No.	57710-80-2
Molecular Formula	C14H11N3O2
Molecular Weight	253.26 g/mol
Synonyms	1-CBZ-Benzotriazole; 1-(Benzyloxycarbonyl)-1H-benzotriazole; Benzyl 1H-Benzotriazole-1-carboxylate; Z-Benzotriazole; Cbz-Bt; 1-Cbz-1H-benzotriazole; 1H-Benzotriazole-1-carboxylic Acid Benzyl Ester; NSC 334365
EINECS	Contact for details

Quality Control

Our 1-(Benzyloxycarbonyl)Benzotriazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.