Description

Methyl 3,4-Di-o-Acetyl-D-Glucuronal is a key protected derivative of D-glucuronic acid, serving as a versatile chiral building block and synthetic intermediate. Its value lies in providing controlled reactivity for the selective synthesis of complex carbohydrates and glycoconjugates. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing novel therapeutics and advanced biomaterials.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of glycosylated drugs, prodrugs, and targeted therapeutic agents.
• Glycochemistry Research: Used as a protected precursor for constructing oligosaccharides, glycoconjugates, and molecular probes.
• Bioconjugation: Enables the site-specific modification of proteins, peptides, and other biomolecules via its reactive functional groups.
• Standards & Reference Materials: Serves as a high-purity analytical standard for method development and quality control in carbohydrate analysis.
• Fine Chemical Synthesis: A chiral synthon for creating specialty chemicals, flavors, and fragrances with specific stereochemistry.

Basic Information

Product Name	Methyl 3,4-Di-o-Acetyl-D-Glucuronal
CAS No.	57690-62-7
Molecular Formula	C11H14O9
Molecular Weight	290.22 g/mol
Synonyms	Methyl (3S,4S,5R,6R)-3,4-Diacetoxy-6-(methoxycarbonyl)-5,6-dihydro-2H-pyran-2-one; Methyl 3,4-Di-O-acetyl-D-glucuronate γ-lactone; D-Glucuronic acid, methyl ester, 3,4-diacetate, γ-lactone; 3,4-Di-O-acetyl-D-glucurono-6,3-lactone methyl ester; Methyl 3,4-di-O-acetyl-D-glucofuranuronate 6,3-lactone
EINECS	Contact for details

Quality Control

Our Methyl 3,4-Di-o-Acetyl-D-Glucuronal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.