Description

(2E,6E)-3,7,11-Trimethyl-9-(Phenylsulfonyl)-2,6,10-Dodecatrienoic Acid Methyl Ester is a specialized synthetic intermediate characterized by its conjugated triene system and phenylsulfonyl functional group. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists working on novel therapeutic agents, vitamin analogs, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of retinoid analogs and other bioactive molecules targeting nuclear receptors.
• Organic Synthesis Building Block: Utilized in carbon-carbon bond-forming reactions, including Michael additions and cyclizations, due to its reactive diene system.
• Medicinal Chemistry Research: Employed in the discovery and development of new chemical entities (NCEs) for oncology, dermatology, and metabolic diseases.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial production of complex target molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2E,6E)-3,7,11-Trimethyl-9-(Phenylsulfonyl)-2,6,10-Dodecatrienoic Acid Methyl Ester
CAS No.	57683-66-6
Molecular Formula	C22H30O4S
Molecular Weight	390.54 g/mol
Synonyms	Methyl (2E,6E)-3,7,11-trimethyl-9-(phenylsulfonyl)-2,6,10-dodecatrienoate; 9-(Phenylsulfonyl)-3,7,11-trimethyl-2,6,10-dodecatrienoic Acid Methyl Ester; (all-E)-3,7,11-Trimethyl-9-(phenylsulfonyl)-2,6,10-dodecatrienoic Acid Methyl Ester; Phenylsulfonyl Retinoate Methyl Ester; Aromatic Sulfone Retinoid Derivative; CAS 57683-66-6
EINECS	Contact for details

Quality Control

Our (2E,6E)-3,7,11-Trimethyl-9-(Phenylsulfonyl)-2,6,10-Dodecatrienoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.