Description

3-Pyridinecarbonyl Chloride, 4-Hydroxy-6-Methyl- (9Ci) is a specialized heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides due to its bioactive pyridine core.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, polymers, and advanced functional coatings.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and enzyme inhibition.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 4-Hydroxy-6-Methyl- (9Ci)
CAS No.	57658-62-5
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	4-Hydroxy-6-methylnicotinoyl chloride; 4-Hydroxy-6-methylpyridine-3-carbonyl chloride; 6-Methyl-4-hydroxynicotinoyl chloride; 3-Carbamoyl-4-hydroxy-6-methylpyridine hydrochloride (precursor related); 4-Hydroxy-6-methyl-3-pyridinecarboxylic acid chloride; Isocarboxyril derivative intermediate
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 4-Hydroxy-6-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.