Description

Diethyl (3-Pyridylmethyl)Malonate is a versatile pyridine-containing malonate ester, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the construction of complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new compounds and scaling up production processes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides that require specific pyridine-based structures for activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances.
• Academic and R&D: A valuable reagent for methodological research in organic chemistry and the discovery of new synthetic pathways.

Basic Information

Product Name	Diethyl (3-Pyridylmethyl)Malonate
CAS No.	57477-12-0
Molecular Formula	C₁₃H₁₇NO₄
Molecular Weight	251.28 g/mol
Synonyms	Diethyl 2-(3-Pyridylmethyl)malonate; Diethyl (3-Pyridinylmethyl)propanedioate; 3-Pyridylmethylmalonic Acid Diethyl Ester; Propanedioic acid, 2-(3-pyridinylmethyl)-, diethyl ester; Diethyl (pyridin-3-ylmethyl)malonate; 3-Pyridinemethylmalonic Acid Diethyl Ester; Diethyl 3-Pyridylmethylmalonate
EINECS	Contact for details

Quality Control

Our Diethyl (3-Pyridylmethyl)Malonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.