Description

[(17S,20R)-5α-Pregnane-3β,11β,17,20,21-Pentyl]Pentakis(Oxy)]Pentakis(Trimethylsilane) is a high-purity, fully protected steroid derivative, specifically designed for advanced synthetic chemistry applications. This compound is critical for researchers and manufacturers requiring precise, multi-step organic synthesis, particularly in the development of complex bioactive molecules. It serves as a key protected intermediate for pharmaceutical R&D, enabling the controlled construction of steroid-based APIs and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Used in academic and industrial laboratories for developing novel synthetic methodologies and constructing intricate molecular architectures.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in steroid analysis.
• Protected Precursor: The pentakis(trimethylsilyl) protection allows for selective deprotection and further functionalization at specific sites on the steroid core.
• Fine Chemical Production: Employed in the manufacture of specialized, high-value steroid derivatives for research and diagnostic applications.

Basic Information

Product Name	[(17S,20R)-5α-Pregnane-3β,11β,17,20,21-Pentyl]Pentakis(Oxy)]Pentakis(Trimethylsilane)
CAS No.	57456-94-7
Molecular Formula	C38H78O5Si5
Molecular Weight	771.5 g/mol
Synonyms	Pregnane-3,11,17,20,21-pentol, pentakis(O-trimethylsilyl) ether, (17α,20R)-isomer; 5α-Pregnane-3β,11β,17,20,21-pentol, pentakis(trimethylsilyl) ether; 3β,11β,17,20,21-Pentakis(trimethylsiloxy)-5α-pregnane; Fully TMS-protected 5α-pregnane pentol; Steroid TMS ether intermediate; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Every batch of [(17S,20R)-5α-Pregnane-3β,11β,17,20,21-Pentyl]Pentakis(Oxy)]Pentakis(Trimethylsilane) is produced and tested under strict quality management systems. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including HPLC, GC, and NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformity to agreed specifications. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this material should be stored under an inert atmosphere (argon or nitrogen) at controlled room temperature (15-25°C). Keep the container tightly sealed in a cool, dry, and well-ventilated place. Minimize exposure to air and moisture to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.