Description

Benzyl Dimethyl Phosphonoacetate is a versatile organophosphorus compound, primarily valued as a key synthetic intermediate in organic chemistry. Its significance lies in its role as a Horner-Wadsworth-Emmons (HWE) reagent, enabling the efficient and stereoselective formation of carbon-carbon double bonds. This makes it an essential building block for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize complex molecules, including active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly for constructing olefin linkages via the Horner-Wadsworth-Emmons reaction.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific alkene functionalities.
• Fine Chemical Production: Serves as a building block for creating specialty chemicals, flavors, fragrances, and advanced material precursors.
• Academic & Industrial Research: A valuable tool in organic synthesis laboratories for method development and the construction of novel organic frameworks.
• Material Science: Potential applications in the synthesis of functionalized polymers and ligands for catalysis.

Basic Information

Product Name	Benzyl Dimethyl Phosphonoacetate
CAS No.	57443-18-2
Molecular Formula	C11H15O5P
Molecular Weight	258.21 g/mol
Synonyms	Dimethyl (benzyloxycarbonylmethyl)phosphonate; (Benzyloxycarbonylmethyl)phosphonic Acid Dimethyl Ester; Phosphonoacetic Acid, Benzyl Ester, Dimethyl Ester; Benzyl (Dimethoxyphosphinyl)acetate; Dimethyl Phosphono(benzyl acetate); HWE Reagent (Benzyl Ester Variant)
EINECS	Contact for details

Quality Control

Our Benzyl Dimethyl Phosphonoacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.