Description

5-Ethyl-1-Methyl-5-[1-Methyl-3-(Trimethylsiloxy)Butyl]-3-(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-protected pyrimidinetrione derivative. This compound is valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis, particularly in the development of complex pharmaceutical molecules. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing modified pyrimidine cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that utilize pyrimidinetrione chemistry.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating complex molecules in custom synthesis and process chemistry projects.
• Protecting Group Chemistry: The trimethylsilyl (TMS) groups provide temporary protection for sensitive functional groups during multi-step synthetic sequences.
• Academic & Industrial R&D: Employed in research laboratories for methodological studies and the exploration of new chemical reactions involving silicon-containing heterocycles.

Basic Information

Product Name	5-Ethyl-1-Methyl-5-[1-Methyl-3-(Trimethylsiloxy)Butyl]-3-(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	57397-42-9
Molecular Formula	C19H38N2O4Si2
Molecular Weight	414.69 g/mol
Synonyms	1,3-Bis(trimethylsilyl)-5-ethyl-1-methyl-5-[1-methyl-3-(trimethylsiloxy)butyl]barbituric acid; 5-Ethyl-1-methyl-5-[1-methyl-3-(trimethylsiloxy)butyl]-3-(trimethylsilyl)barbituric acid; 1,3-Bis-O-trimethylsilyl-5-ethyl-1-methyl-5-[1-methyl-3-(trimethylsiloxy)butyl]barbituric acid; TMS-protected barbiturate derivative; Silicon-modified pyrimidinetrione
EINECS	Contact for details

Quality Control

Our production of 5-Ethyl-1-Methyl-5-[1-Methyl-3-(Trimethylsiloxy)Butyl]-3-(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.