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2-O,3-o-Dimethyl-5-O,6-o-Bis(Trimethylsilyl)-D-Ascorbic Acid CAS NO 57397-28-1


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CAS No.:57397-28-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-O,3-o-Dimethyl-5-O,6-o-Bis(Trimethylsilyl)-D-Ascorbic Acid is a chemically modified, silyl-protected derivative of D-ascorbic acid. This compound is engineered to provide enhanced stability and solubility in organic media, making it a valuable intermediate for advanced synthetic chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers for the development of novel compounds, including prodrugs and specialty fine chemicals.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and prodrugs requiring protected ascorbic acid moieties.
  • Organic Synthesis Reagent: Used in reactions where a protected, non-acidic form of ascorbic acid is required to prevent unwanted side reactions.
  • Research & Development: Serves as a critical reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.
  • Fine Chemical Production: Employed in the manufacture of specialty chemicals, including antioxidants and stabilizers with tailored properties.
  • Cosmetic Ingredient Synthesis: Used as a precursor in developing stabilized vitamin C derivatives for advanced skincare formulations.

Basic Information

Product Name 2-O,3-o-Dimethyl-5-O,6-o-Bis(Trimethylsilyl)-D-Ascorbic Acid
CAS No. 57397-28-1
Molecular Formula C14H30O6Si2
Molecular Weight 350.56 g/mol
Synonyms D-Ascorbic Acid 5,6-Bis(trimethylsilyl) 2,3-dimethyl ether; 5,6-Bis-O-(trimethylsilyl)-2,3-di-O-methyl-D-erythro-hex-2-enono-1,4-lactone; 2,3-Di-O-methyl-5,6-bis-O-(trimethylsilyl)-D-ascorbic acid; Protected D-Ascorbic Acid Derivative; Silylated D-Isoascorbic Acid Derivative; D-Erythorbic Acid 5,6-bis(trimethylsilyl) ether 2,3-dimethyl ether
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Quality Control

Our 2-O,3-o-Dimethyl-5-O,6-o-Bis(Trimethylsilyl)-D-Ascorbic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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