Description

2-O,3-o-Dimethyl-5-O,6-o-Bis(Trimethylsilyl)-L-Ascorbic Acid is a chemically modified, silyl-protected derivative of L-ascorbic acid (Vitamin C), designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring a stabilized, reactive intermediate that protects sensitive hydroxyl groups during complex organic synthesis. It is primarily utilized in the pharmaceutical, nutraceutical, and fine chemical industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key protected building block in the multi-step synthesis of complex drug molecules, particularly those derived from vitamin C.
• Asymmetric Synthesis: Used in stereoselective reactions where the chiral integrity of the L-ascorbic acid scaffold must be preserved.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including advanced antioxidants and functional materials.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel molecular entities.
• Glycosylation Reactions: Acts as a glycosyl donor precursor or a chiral auxiliary in carbohydrate chemistry.
• Prodrug Development: Utilized to create lipophilic prodrug forms of ascorbic acid to enhance bioavailability or targeting.

Basic Information

Item	Details
Product Name	2-O,3-o-Dimethyl-5-O,6-o-Bis(Trimethylsilyl)-L-Ascorbic Acid
CAS No.	57397-26-9
Molecular Formula	C14H30O6Si2
Molecular Weight	350.56 g/mol
Synonyms	2,3-O-Dimethyl-5,6-O-bis(trimethylsilyl)-L-ascorbic acid; 2,3-Di-O-methyl-5,6-di-O-trimethylsilylascorbic acid; Protected L-Ascorbic Acid Derivative; TMS-protected Ascorbic Acid; Vitamin C Silyl Ether Derivative; L-Ascorbic acid 2,3-dimethyl-5,6-bis(trimethylsilyl) ether; 5,6-Bis-O-(trimethylsilyl)-2,3-di-O-methyl-L-ascorbic acid
EINECS	Contact for details

Quality Control

Our 2-O,3-o-Dimethyl-5-O,6-o-Bis(Trimethylsilyl)-L-Ascorbic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.