Description

Silane, [[(3Alpha,5Beta,11Beta,20R)-Pregnane-3,11,17,20-Tetrayl]Tetrak Is(Oxy)]Tetrakis*Trimethyl- is a specialized organosilicon derivative of a pregnane steroid backbone. This compound is valued for its role as a key synthetic intermediate and functionalization agent in advanced organic and organometallic chemistry. It is primarily required by research and development laboratories and production facilities in the pharmaceutical and fine chemical sectors. The precise functionalization offered by this silane makes it critical for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel steroid-based active pharmaceutical ingredients (APIs) and drug candidates.
• Chemical Derivatization Agent: Used to introduce silyl protecting groups or to functionalize steroid molecules at specific hydroxyl sites for further chemical transformations.
• Advanced Material Research: Employed in the development of steroidal liquid crystals, hybrid organic-inorganic materials, or surface-modifying agents due to its reactive silane groups.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for high-value steroid derivatives in pilot plant and manufacturing settings.
• Analytical Standard: Acts as a reference standard in chromatographic (HPLC, GC) and spectroscopic (NMR, MS) analysis for quality control and method development.

Basic Information

Product Name	Silane, [[(3Alpha,5Beta,11Beta,20R)-Pregnane-3,11,17,20-Tetrayl]Tetrak Is(Oxy)]Tetrakis*Trimethyl-
CAS No.	57397-17-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	[[(3α,5β,11β,20R)-Pregnane-3,11,17,20-tetrayl]tetrakis(oxy)]tetrakis[trimethylsilane]; Tetrakis-O-(trimethylsilyl) Derivative of (3α,5β,11β,20R)-Pregnane-3,11,17,20-tetrol; Pregnane-3,11,17,20-tetrol Tetrakis(trimethylsilyl) Ether; TMS Ether of Pregnane Tetrol; Steroid TMS Derivative; 57397-17-8; (3α,5β,11β,20R)-3,11,17,20-Tetrakis[(trimethylsilyl)oxy]pregnane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for parameters such as assay (by HPLC or NMR), identity (IR, NMR), and purity profile are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.