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17-Methyl-17-[(Trimethylsilyl)Oxy]Androsta-1,4-Dien-3-One o-Methyloxim E CAS NO 57397-03-2


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CAS No.:57397-03-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

17-Methyl-17-[(Trimethylsilyl)Oxy]Androsta-1,4-Dien-3-One o-Methyloxim E is a high-purity, advanced steroid derivative featuring a trimethylsilyl-protected hydroxyl group and an o-methyloxime modification. This compound is critical for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting endocrine pathways. It serves as a key synthetic intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise molecular architecture.

Application

  • Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel steroid-based pharmaceuticals and active pharmaceutical ingredients (APIs).
  • Endocrinology Research: Used in academic and industrial laboratories to study hormone receptor interactions and develop new modulators.
  • Metabolic Pathway Studies: Employed as a probe or precursor in biochemical research to investigate steroid metabolism and enzymatic transformations.
  • Process Development: Serves as a reference standard and starting material for scaling up and optimizing synthetic routes in process chemistry.
  • Fine Chemical Synthesis: Utilized in the preparation of specialized, high-value chemical entities for advanced material science and agrochemical research.

Basic Information

Item Details
Product Name 17-Methyl-17-[(Trimethylsilyl)Oxy]Androsta-1,4-Dien-3-One o-Methyloxim E
CAS No. 57397-03-2
Molecular Formula C24H39NO2Si
Molecular Weight 401.66 g/mol
Synonyms 17-Methyl-17-[(trimethylsilyl)oxy]androsta-1,4-dien-3-one O-methyloxime; 57397-03-2; Androsta-1,4-dien-3-one, 17-methyl-17-[(trimethylsilyl)oxy]-, O-methyloxime; 17β-Methyl-17α-[(trimethylsilyl)oxy]androsta-1,4-dien-3-one O-methyloxime; 17-Methyl-17-trimethylsilyloxyandrosta-1,4-dien-3-one O-methyloxime; TMS-protected steroid oxime derivative
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Quality Control

Our 17-Methyl-17-[(Trimethylsilyl)Oxy]Androsta-1,4-Dien-3-One o-Methyloxim E is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Any single unknown impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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