Description

1,3-Dimethyl-5-Phenyl-5-[1-(Trimethylsiloxy)Ethyl]-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon derivative of a barbituric acid analog, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in the unique reactivity imparted by the trimethylsiloxyethyl group, which can act as a protected alcohol or a silyl enol ether precursor. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and synthesis of novel therapeutic agents, particularly those with complex heterocyclic cores.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its structural motifs can contribute to biological activity.
• Organosilicon Chemistry Research: Serves as a model compound for studying the reactivity and applications of silicon-containing organic molecules in synthesis.
• Material Science Precursor: Potential use in the development of specialty polymers or organic electronic materials due to its multifunctional structure.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and exploratory chemistry projects.

Basic Information

Product Name	1,3-Dimethyl-5-Phenyl-5-[1-(Trimethylsiloxy)Ethyl]-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	57396-65-3
Molecular Formula	C₁₇H₂₄N₂O₄Si
Molecular Weight	348.47 g/mol
Synonyms	5-Phenyl-1,3-dimethyl-5-[(trimethylsilyloxy)methyl]barbituric Acid; 5-[1-(Trimethylsiloxy)ethyl]-5-phenyl-1,3-dimethylbarbituric Acid; 1,3-Dimethyl-5-phenyl-5-[(trimethylsilyloxy)methyl]-2,4,6-pyrimidinetrione; TMS-Ethyl Phenyl Dimethyl Barbiturate; Siloxyethyl Phenyl Dimethyl Barbiturate; NSC 339063; Barbituric acid, 5-phenyl-1,3-dimethyl-5-[(trimethylsilyloxy)methyl]-
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-5-Phenyl-5-[1-(Trimethylsiloxy)Ethyl]-2,4,6(1H,3H,5H)-Pyrimidinetrione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.