Description

4-Fluoropiperidine Hydrochloride is a high-purity fluorinated piperidine derivative, a crucial building block in modern synthetic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce fluorine atoms or piperidine motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the fluoropiperidine moiety enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design of molecular probes and fluorinated analogs for studying biological pathways and enzyme inhibition.
• Material Science Research: Acts as a monomer or functional additive in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	4-Fluoropiperidine Hydrochloride
CAS No.	57395-89-8
Molecular Formula	C5H11ClFN
Molecular Weight	139.60 g/mol
Synonyms	4-Fluoropiperidine HCl; 4-Fluoro-piperidine hydrochloride; Piperidine, 4-fluoro-, hydrochloride; 4-Fluoropiperidinium chloride; 4-Fluoropiperidine monohydrochloride; 4-Fluoro-1-azacyclohexane hydrochloride; 4-F-Pip·HCl
EINECS	Contact for details

Quality Control

Our 4-Fluoropiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.