Description

[(20R)-5α-Pregnane-3α,11β,20,21-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane) is a high-purity, organosilicon-protected steroid derivative of significant synthetic utility. This compound is valued for its role as a key synthetic intermediate, enabling the controlled functionalization of the pregnane backbone in complex organic syntheses. It is primarily required by research institutions and pharmaceutical development laboratories engaged in the synthesis of novel steroid-based compounds, including potential drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex steroid molecules for medicinal chemistry research and development.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in steroid analysis.
• Organic Synthesis Reagent: Serves as a protected precursor in organic synthesis, allowing for selective reactions at other sites of the steroid nucleus.
• Biochemical Research: Employed in studies investigating steroid metabolism, receptor interactions, and the development of enzyme inhibitors.
• Process Chemistry: Utilized in the development and scale-up of synthetic routes for steroid-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	[(20R)-5α-Pregnane-3α,11β,20,21-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane)
CAS No.	57363-12-9
Molecular Formula	C40H84O4Si4
Molecular Weight	741.5 g/mol
Synonyms	5α-Pregnane-3α,11β,20,21-tetrayl Tetraacetate Tetrakis(trimethylsilyl) Ether; 3α,11β,20,21-Tetrakis(trimethylsilyloxy)-5α-pregnane; Pregnane-3α,11β,20,21-tetrol Tetrakis-O-(trimethylsilyl) Ether; TMS-protected Pregnane Tetrol; Steroid TMS Ether Derivative; 57363-12-9; Tetrakis(trimethylsilyl) Ether of Pregnane-3α,11β,20,21-tetrol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system suitable for supplying materials for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.