Description

1,3-Dimethyl-5-[2-Oxo-3-(Trimethylsiloxy)Propyl]-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized, high-value pyrimidinetrione derivative featuring a reactive trimethylsiloxypropyl side chain. This compound is significant as a key synthetic intermediate or building block in advanced organic synthesis, particularly for the development of complex heterocyclic molecules. It is primarily needed by research and development laboratories, pharmaceutical companies, and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and other performance chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Research: Used in the development of new pesticides, herbicides, or fungicides where the pyrimidinetrione scaffold can impart specific biological activity.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating specialty chemicals, dyes, pigments, or advanced materials with tailored properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for methodological studies, library synthesis, and exploring new chemical reactions involving silyl-protected functional groups.
• Process Chemistry Development: Utilized in scaling up synthetic routes from lab to pilot plant, where consistent quality and reliable supply of this intermediate are critical.

Basic Information

Product Name	1,3-Dimethyl-5-[2-Oxo-3-(Trimethylsiloxy)Propyl]-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	57346-74-4
Molecular Formula	C18H24N2O5Si
Molecular Weight	376.48 g/mol
Synonyms	5-[2-Oxo-3-(Trimethylsiloxy)propyl]-1,3-dimethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione; 1,3-Dimethyl-5-phenyl-5-(3-trimethylsilanyl-2-oxo-propyl)-pyrimidine-2,4,6-trione; Barbituric acid, 1,3-dimethyl-5-phenyl-5-[2-oxo-3-[(trimethylsilyl)oxy]propyl]-; 5-Phenyl-5-(3-trimethylsilyl-2-oxopropyl)-1,3-dimethylbarbituric acid; Silylated Barbiturate Derivative; CAS 57346-74-4
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-5-[2-Oxo-3-(Trimethylsiloxy)Propyl]-5-Phenyl-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.