Description

Pregnan-20-One, 3,11,21-Tris[(Trimethylsilyl)Oxy]-, o-(Phenylmethyl)Ox Ime, (3Beta,5Alpha,11Beta)- is a high-purity, advanced steroid derivative, specifically designed for research and development in complex organic synthesis. This compound is valued for its role as a key protected intermediate, enabling precise chemical transformations in the production of specialized pharmaceutical actives and reference standards. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in regulatory submissions.
• Process Chemistry Research: Enables exploration of novel synthetic pathways and the development of more efficient manufacturing processes for corticosteroid analogs.
• Biochemical Research: Serves as a precursor or analog in studies investigating steroid hormone receptors, metabolism, and biological activity.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialized, high-value compounds for academic and industrial research projects.

Basic Information

Product Name	Pregnan-20-One, 3,11,21-Tris[(Trimethylsilyl)Oxy]-, o-(Phenylmethyl)Ox Ime, (3Beta,5Alpha,11Beta)-
CAS No.	57325-99-2
Molecular Formula	C36H60O6Si3
Molecular Weight	697.1 g/mol
Synonyms	(3β,5α,11β)-20-Oxo-3,11,21-tris[(trimethylsilyl)oxy]pregnan-18-yl benzoate; 18-Benzoyloxy-3,11,21-tris(trimethylsiloxy)-5α-pregnan-20-one; 3β,11β,21-Tris(trimethylsiloxy)-5α-pregnan-20-one 18-benzoate; Pregnane-20-one, 3,11,21-tris[(trimethylsilyl)oxy]-, o-(phenylmethyl) oxime, (3β,5α,11β)-; TMS-protected 18-benzoyloxycorticosterone derivative.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and compliance with research-grade specifications. Our quality protocols are designed to support GMP-aligned development and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.